Alabama rot, medically known as cutaneous and renal glomerular vasculopathy (CRGV), is a rare but serious condition that affects dogs in the United States. First identified in Greyhounds in Alabama during the 1980s, the disease has since been documented primarily in the US and also notably in the UK since 2012. Despite its rarity, it has sparked considerable concern among dog owners due to its severity and sudden onset.
Although the exact cause is still not fully understood, veterinary research points to environmental factors playing a crucial role. This article aims to clarify what is known about Alabama rot, dispelling myths and sharing practical guidance to help you protect your dog.
Alabama rot causes damage to small blood vessels in the skin and kidneys, which leads to painful skin sores and ulcerations, followed in some cases by acute kidney failure. The disease progresses quickly and is often fatal without swift medical treatment.
The cases tend to be clustered during colder and wetter months, with many reported in the fall through early spring, matching periods of increased dampness. Any dog, regardless of breed or age, can be affected. There is no evidence that any breed has natural immunity.
While exact nationwide case numbers are limited due to the disease’s rarity, thousands of dogs live in environments where risk factors are present. Specific hotspots in the US include wooded or muddy areas, often those frequented by outdoor enthusiasts, hunters, and hikers.
The root cause of Alabama rot remains elusive, but scientific studies up to 2024 suggest a bacterial involvement, particularly Escherichia coli, combined with environmental triggers. Dogs’ exposure to muddy ground, fallen leaves, and wet woodland soil appears to increase the risk.
Not all dogs walking in such conditions develop the disease, highlighting that other unknown factors, including genetic predisposition or immune response, may influence susceptibility. Research continues to explore these interactions.
Initial symptoms typically include red, swollen, or ulcerated skin lesions. These sores are commonly found on a dog’s legs below the elbows or knees, but can also appear on the chest, abdomen, or muzzle. Dogs may lick or chew at these areas more than usual.
Within a few days, if kidney involvement occurs, signs such as vomiting, decreased appetite, lethargy, and behavioral changes may develop. If you notice these symptoms, immediate consultation with a licensed veterinarian is essential for diagnosis and early intervention.
The outlook for dogs diagnosed with Alabama rot can be poor due to the extent of kidney damage that often follows. Unfortunately, mortality rates are high, with studies suggesting that up to 90% of affected dogs may not survive if kidney failure ensues.
However, a minority of dogs have recovered following aggressive supportive care. New treatments such as plasma exchange and intensive care protocols available at specialized veterinary hospitals show encouraging promise, but early detection remains critical.
No vaccine currently exists for Alabama rot, and prevention relies on awareness and minimizing risk. Here are some practical recommendations:
These simple steps, coupled with regular veterinary visits, can help responsibly reduce your dog’s risk while still enjoying nature.
Current evidence shows Alabama rot affects only dogs and is not contagious between dogs nor transmissible to other animals like cats or humans.
The condition is considered a non-infectious disease linked specifically to environmental exposure rather than direct transmission. So, multi-pet households should remain alert for symptoms in dogs but can feel reassured regarding other pets and people.
Alabama rot is a rare but severe disease primarily seen in American dogs that can cause devastating health consequences. It is associated with certain environmental exposures and seasonal timing, yet affects dogs of all breeds and ages indiscriminately.
Early detection of skin lesions, prompt veterinary attention, and sensible precautions during high-risk periods provide the best protection. Although the prognosis is generally guarded, recent medical advances encourage hope for affected dogs with timely care.
Keeping informed, staying watchful, and acting quickly are key to responsible dog ownership in the face of this challenging condition.
For example, popular outdoor spots in the Pacific Northwest and parts of the Northeast with heavy rainfall and muddy trails are commonly associated with higher risk, where dog owners should be especially cautious to protect their pets.
In addition, breeds frequently found across the US—including the highly popular Labrador Retriever puppies and Golden Retriever puppies—do not have resistance and should be monitored carefully.