Bandera's Syndrome, also known as Bandera's Neonatal Cerebellar Ataxia (BNAt), is a genetic neurological disorder primarily found in Coton de Tulear puppies. This inherited condition targets the cerebellum, the area of the brain that manages coordination and balance, resulting in serious motor function impairments.
This disorder stems from a mutation in glutamate receptor genes, which are critical for a puppy's development of walking and basic skills like standing, eating, and bathroom habits. Bandera's Syndrome is inherited through a recessive gene pattern, meaning a pup must receive two defective genes—one from each parent—to develop the condition. Dogs carrying one copy often show no signs but breeding two carriers can produce affected puppies. In the United States, responsible breeders of the Coton de Tulear frequently perform genetic testing to prevent the spread of this disorder.
Puppies with Bandera's Syndrome may seem healthy at first, nursing properly and gaining weight. However, beginning around the third week, they develop clumsy, swimming-like leg movements, difficulty standing, intention tremors causing head shaking when focusing, and abnormal eye movements. These symptoms impair their ability to move, eat, drink, and eliminate without help, making full-time care necessary.
If a puppy displays signs of neurological dysfunction, a thorough evaluation by a veterinarian is essential. Diagnosis often involves excluding other conditions such as trauma or infections. Genetic testing is the definitive method to confirm Bandera's Syndrome by detecting the specific gene mutation. Unfortunately, no treatment exists, and humane euthanasia is often recommended by U.S. veterinarians to prevent prolonged suffering in affected dogs.
Preventative measures are key to controlling Bandera's Syndrome. DNA testing all breeding Coton de Tulear dogs helps avoid mating two carriers. Ethical breeders in the U.S. prioritize routine genetic screening for stud dogs and puppies alike to protect breed health. This careful breeding approach prevents the transmission of this lethal hereditary disease, securing the breed’s future.
Gaining knowledge about Bandera's Syndrome equips breeders and pet owners with the tools to act responsibly. If you are considering finding a Coton de Tulear puppy, it’s vital to work with reputable breeders who commit to genetic testing and ethical practices. Through collaboration, we can help ensure healthy puppies and reduce hereditary disorders like Bandera's Syndrome in the breed.