Hyperkeratosis in Dogs: Causes, Testing & Care Tips

Hyperkeratosis in dogs is a skin disorder where portions of the nose or paw pads become thickened and hardened due to an overproduction of keratin. Not all dogs display symptoms in both areas; some develop this condition primarily on their nose or feet.

This skin issue is often inherited, particularly in breeds such as the Dogue de Bordeaux puppies, Irish Terrier, and Kromfohrländer. It can also arise secondary to other ailments like canine distemper or zinc-responsive dermatosis. In the U.S., responsible breeders may opt for genetic screening to identify carriers of Hereditary Footpad Hyperkeratosis (HFH) to help limit cases.

In this article, we delve into hyperkeratosis’s root causes, genetic testing approaches, prevention strategies, and ways to manage it, aiming to ensure your dog’s comfort and well-being.

What Exactly is Hyperkeratosis?

This condition results in unusually thick, hardened patches of skin on a dog's nose (nasal hyperkeratosis) or paw pads (foot pad keratosis). An excessive build-up of keratin, the protein that forms skin structure, leads to rough, dry, and often cracked skin, which might cause discomfort or pain.

Cracked skin creates an entry point for infections. When paws are affected, it can impair your dog’s ability to walk comfortably. Additionally, the claws might grow irregularly because of the paw pad changes.

Root Causes of Hyperkeratosis in Dogs

The condition generally develops due to one of two main factors:

• Genetic predisposition—more common in certain breeds with a hereditary tendency. Testing breeding dogs for HFH is encouraged in the U.S. among informed breeders.
• Secondary hyperkeratosis—occurs as a result of other health conditions, such as distemper, pemphigus foliaceus, leishmaniasis, or zinc deficiency-related dermatosis.

How Hyperkeratosis is Passed Down Genetically

Hereditary Footpad Hyperkeratosis follows an autosomal recessive inheritance pattern. This means:

• If both parents are tested clear, none of the puppies will be affected.
• If one parent is a carrier while the other is clear, puppies have a 50% chance of being carriers but will not show symptoms.
• If both parents are carriers, there’s a 25% chance puppies will be affected, 50% chance they will be carriers, and 25% will be clear.
• If one parent is affected, all offspring will be at least carriers, and some may be affected.

Genetic Testing for Hyperkeratosis in the U.S.

In the American dog breeding community, genetic testing for hyperkeratosis is less widespread than for other hereditary diseases. However, some breeders of at-risk breeds like the Dogue de Bordeaux and Irish Terrier pursue DNA testing to identify carriers and affected dogs to help make responsible breeding choices.

Such testing, although not mandatory nationwide, supports reducing incidence and improves overall breed health by avoiding at-risk pairings.

Preventing Hyperkeratosis

While you cannot prevent hereditary hyperkeratosis in a dog already affected, DNA screening and careful breeding decisions minimize its future occurrence. Moreover, effectively managing other illnesses that might cause secondary hyperkeratosis reduces risk.

Managing and Treating Hyperkeratosis

Although hyperkeratosis has no cure, proper treatment can control symptoms and enhance canine comfort:

• Routine veterinary visits for trimming away excess thick skin, especially on paw pads.
• Daily application of moisturizing balms or ointments to keep skin supple and limit cracking.
• Prompt treatment of any infections at cracked or damaged skin areas.
• Providing soft, cushioned bedding and avoiding excessive pressure or abrasion on affected parts.

Good care and monitoring enable affected dogs to maintain mobility and happiness despite the condition.

FAQs on Canine Hyperkeratosis

Which dog breeds are most likely to develop hyperkeratosis?

Breeds at increased hereditary risk include the Dogue de Bordeaux, Irish Terrier, and Kromfohrländer. In the U.S., popular brachycephalic breeds like English Bulldogs and French Bulldogs also commonly develop nasal hyperkeratosis due to their facial build.

How do veterinarians diagnose hyperkeratosis?

Veterinarians diagnose this condition through physical examination, noting the presence of thickened, hard patches and cracks in the skin. Genetic testing can help confirm hereditary cases. Occasionally, a skin biopsy is necessary to exclude other skin diseases.

Is hyperkeratosis painful for dogs?

Yes, the thickened skin can crack, causing pain and heightened vulnerability to infections — particularly in affected paw pads, which may interfere with walking.

Can hyperkeratosis spread between dogs?

No, hyperkeratosis is not contagious. It results from genetic factors or is a secondary symptom of other health disorders rather than an infectious agent.

Conclusion

Whether hereditary or secondary, hyperkeratosis is a canine skin condition requiring attention to keep your dog comfortable and healthy. Genetic testing among breeders helps prevent the spread of hereditary cases. With ongoing veterinary care and proper management, dogs living with hyperkeratosis can enjoy a good quality of life.

If you notice signs of thickened, cracked skin on your dog’s nose or paws, consult your veterinarian for diagnosis and treatment recommendations. Being a responsible dog owner and breeder through awareness and care significantly benefits your pet.