Mastiff Dog Health: Hereditary Issues & Testing Guide

The Mastiff is a grand and striking large dog breed, typically standing up to 30 inches tall and weighing as much as 240 pounds. Celebrated for their gentle temperament and protective instincts, Mastiffs need plenty of room and a knowledgeable owner to truly meet their distinct needs. Understanding the breed’s inherited health challenges and the recommended health screenings is crucial for anyone planning to welcome a Mastiff into their American home.

"Mastiff" is a broad term often used not only to describe the classic Mastiff breed but also to classify several Molosser-type breeds that include "mastiff" in their names. These dogs commonly share traits like a wide skull, deep chest, and muscular frame. This guide specifically covers hereditary health concerns and testing related to the Mastiff breed as recognized in the United States.

Genetic Diversity and Responsible Breeding Practices in the USA

The coefficient of inbreeding (COI) for Mastiffs in the US tends to be around 13.3%, which exceeds the ideal limit of 6.25% recommended for purebred dogs to maintain genetic diversity. This higher COI suggests a heightened risk of hereditary diseases due to limited gene pool variability. Dedicated American breeders work hard to keep this figure as low as possible by carefully selecting mates and applying genetic tests, securing the breed's future health and vitality.

Common Hereditary Health Problems Affecting Mastiffs

Mastiffs have a predisposition to several inherited health issues. Being aware of these conditions helps prospective owners and breeders implement preventive actions and appropriate health evaluations.

• Hip Dysplasia: A primary concern is poor hip joint formation. The average hip score for Mastiffs can be about 18.5, which is considered high, indicating potential problems. Reputable breeding dogs ideally score below this threshold to minimize the chance of passing hip-related issues.
• Elbow Dysplasia: This joint disease affects the elbows, potentially causing pain and difficulty moving; early screening is critical.
• Progressive Retinal Atrophy (PRA): A genetic eye condition that results in gradual vision loss; DNA testing identifies carriers to prevent passing the gene.
• Multifocal Retinopathy: Another retina disorder detectable through genetic tests, impacting vision health.
• Thyroid Disorders: Autoimmune thyroiditis can affect energy and metabolism in Mastiffs.
• Cystinuria: This hereditary condition causes kidney and bladder stones due to abnormal amino acid excretion; DNA testing confirms its presence.
• Degenerative Myelopathy (DM): A progressive spinal disease leading to worsening coordination and mobility loss, significant among Mastiffs and screened genetically.
• Bloat (Gastric Dilatation-Volvulus): Due to their deep chest, Mastiffs face an increased risk of this critical, life-threatening emergency where the stomach twists; prompt veterinary attention is vital.

Recommended Health Testing for Mastiffs in the USA

The American Kennel Club (AKC), the Orthopedic Foundation for Animals (OFA), and other respected organizations recommend these health screenings to support Mastiff wellbeing:

• Radiographic hip and elbow scoring to assess joint structure, commonly documented by OFA certifications.
• Genetic testing for hereditary eye diseases, including PRA and multifocal retinopathy.
• Cardiac exams to evaluate for heart anomalies such as pulmonic stenosis or mitral valve dysplasia.
• DNA screening for cystinuria, degenerative myelopathy, and related genetic disorders.
• Testing for Von Willebrand Disease Type I and hyperuricosuria (HUU), which can also occur in Mastiffs.
• Responsible breeding recommends females be bred only between 20 months and 6 years old to encourage healthier litters.

Given the Mastiff’s sensitive health profile, the breed is classified as a high-priority breed by American breeding clubs, underscoring the importance of thorough health management and continued genetic research.

Additional Care Tips for Mastiff Owners

Beyond genetic concerns, daily maintenance is crucial to keep Mastiffs healthy:

• Their distinctive facial skin folds need frequent cleaning and drying to avoid bacterial infections common in moist environments.
• Puppies and young Mastiffs should avoid excessive exercise to protect developing joints and bones.
• Keep a close eye for signs like swelling, limping, or unusual eye symptoms to ensure early intervention by your American veterinarian.

Finding a Healthy Mastiff Puppy in the USA

If you are looking to find an English Mastiff puppy, it is essential to work with reputable Mastiff breeders who prioritize genetic screening and responsible breeding. Trustworthy breeders will provide comprehensive health documentation, including genetic test results, offering peace of mind about your new family member’s long-term health prospects.

Summary

The Mastiff’s grandeur and devoted nature make it a rewarding pet for those prepared to meet its special requirements. Understanding hereditary health conditions such as hip and elbow dysplasia, degenerative myelopathy, eye disorders, and bloat is essential. Supporting recommended health testing and obtaining puppies from responsible American breeders improves the breed’s welfare and longevity. Investing in this knowledge helps ensure your Mastiff enjoys a vibrant and joyful life by your side.