Megaoesophagus (MO) is a condition in dogs where the esophagus loses its muscle tone and becomes enlarged, making it challenging for food to travel from the mouth to the stomach. Normally, the esophagus uses rhythmic contractions called peristalsis to push food down. When these muscles fail, the esophagus becomes weak and dilated, causing food to build up and often be regurgitated. This disorder affects several breeds, including the Irish Setter. It can be congenital (present at birth) or develop later in life.