Big Great Dane Puppies for sale Nationwide

Handsome playful and charming

Meet Ronald Weasley a big ole happy, calm, and smart boy. -LancasterPuppies

Meet Eleven this sweet, beautiful, harlequin pie is just as big as the boys, she is the only female in her liter and just like in stranger things she is one cool chicka. -LancasterPuppies

Meet Ginny Weasley, A sweet, smart, and calm beautiful girl. She is a properly marked Mantle who will be a big girl who is smart and loyal to her family. -LancasterPuppies

Meet Luna lovegood, A big beautiful female who loves attention and affection. -LancasterPuppies

HOW IS THIS BOY STILL AVAILABLE! Dipper is going to be a big boy just like his daddy! This boy is sweet, affectionate and adventurous, the perfect puppy!

“Dakota” is a blue boy with only a small white line on his chest and solid blue toes. He is a high content Euro Great Dane that comes from danes of great height and heft. Our blue’s are so shiny!

Alabama “BIG Al’ is a beautiful all black euro line Great Dane that is going to be an amazing looking Dane. We love our black Danes! Although is a solid black, Al carries for many colors in his back

He's going to be very big. He has unique coloring and markings that will give him a different look from any other dog.

She's going to be a big girl and loves to cuddle!

He's going to be a big boy that will be your new best friend!

She's going to be a big girl, but right now she just wants to cuddle!

Blue Merlequin Female Love bug

Ready to go now - 4 adorable pups ready to find their forever homes! All of them are up to date on shots and have been dewormed. First month of Heart- and Nexguard has been given. All have been well

A big male merle. He's big and chill boy. For better pics and video text ************ Amber.

Blue Harlequin Male Sweetest disposition

DFW, Texas 10 half Euro/half American Great Dane puppies Available 1/29/26. Birth date 12/4/25. 5 girls and 5 boys. 3 rounds of Deworm. First Vaccine. Both Parents on site. PM for info. Father is 16 m

DFW, Texas 10 half Euro/half American Great Dane puppies Available 1/29/26. Birth date 12/4/25. 5 girls and 5 boys. 3 rounds of Deworm. First Vaccine. Both Parents on site. PM for info. Father is 16 m

DFW, Texas 10 half Euro/half American Great Dane puppies Available 1/29/26. Birth date 12/4/25. 5 girls and 5 boys. 3 rounds of Deworm. First Vaccine. Both Parents on site. PM for info. Father is 16 m

DFW, Texas 10 half Euro/half American Great Dane puppies Available 1/29/26. Birth date 12/4/25. 5 girls and 5 boys. 3 rounds of Deworm. First Vaccine. Both Parents on site. PM for info. Father is 16 m

DFW, Texas 10 half Euro/half American Great Dane puppies Available 1/29/26. Birth date 12/4/25. 5 girls and 5 boys. 3 rounds of Deworm. First Vaccine. Both Parents on site. PM for info. Father is 16 m

A big male harlequin. He's big and playful. For better pics and video text ************ Amber.

A big male harlequin with blue eyes. He's big and playful. For better pics and video text ************ Amber.

Ready to go now - 4 adorable pups ready to find their forever homes! All of them are up to date on shots and have been dewormed. First month of Heart- and Nexguard has been given. All have been well

Another big black girl with a shield emblem on her chest. She is our bravest. For better pics and video text ************ Amber.

DFW, Texas 10 half Euro/half American Great Dane puppies Available 1/29/26. Birth date 12/4/25. 5 girls and 5 boys. 3 rounds of Deworm. First Vaccine. Both Parents on site. PM for info. Father is 16 m

DFW, Texas 10 half Euro/half American Great Dane puppies Available 1/29/26. Birth date 12/4/25. 5 girls and 5 boys. 3 rounds of Deworm. First Vaccine. Both Parents on site. PM for info. Father is 16 m

Blue Merlequin Female Sweet and calm

Our big harlequin girl. She's the boss of the litter. She's afraid of nothing. For better pics and video text ************ Amber

DFW, Texas 10 half Euro/half American Great Dane puppies Available 1/29/26. Birth date 12/4/25. 5 girls and 5 boys. 3 rounds of Deworm. First Vaccine. Both Parents on site. PM for info. Father is 16 m

DFW, Texas 10 half Euro/half American Great Dane puppies Available 1/29/26. Birth date 12/4/25. 5 girls and 5 boys. 3 rounds of Deworm. First Vaccine. Both Parents on site. PM for info. Father is 16 m

DFW, Texas 10 half Euro/half American Great Dane puppies Available 1/29/26. Birth date 12/4/25. 5 girls and 5 boys. 3 rounds of Deworm. First Vaccine. Both Parents on site. PM for info. Father is 16 m

A very big girl. For better pics and video text ************ Amber.

Another big girl. Mostly white with some spots. She's very friendly. For better pics and video text ************ Amber.

This is our big boy, such a loving! Baby, he’s so chill and just a lap dog

Tnis is our big girl and just like her brother and you cant see in the picture but she has what looks like a heart mark on her chest

He’s our our little guy not as big as his big brother but is just as sweet, he has the biggest personality! Loves to be sooner of attention

Harlequin Male Largest of litter