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Great Dane mix Puppies for sale

33 Puppies found

The Great Dane is often called the “gentle giant” of the dog world, admired for its towering stature and calm, affectionate personality. Descended from ancient Molossus war dogs and refined in Germany to hunt wild boar, the breed later became a symbol of elegance and nobility. With their sleek, muscular build, graceful posture, and loyal temperament, Great Danes combine regal appearance with a sweet, patient nature that makes them beloved family companions.

Despite their massive size, Great Danes are gentle, friendly, and eager to please. They thrive on human companionship and are known for being affectionate with children and sociable with other pets. Protective when needed but never aggressive, they make excellent watchdogs as well. Their short coat requires only weekly brushing, and moderate daily exercise keeps them healthy and happy. With their kind spirit and noble presence, Great Danes bring both majesty and warmth to any home.

Mixed Breed dogs Pink-Full Brindle - Ad 1
Mixed Breed dogs Pink-Full Brindle - Ad 2
BOOST
22

Pink-Full Brindle

Great Dane & Labrador Retriever hybrid

7 weeksAge
FemaleSex
$2,000Price

Mother (Cami's) 2nd litter who is a Brindle Great Dane, Gentle, Great Mama, Very loving, obedient & loyal. All pups just like 1st litter will be vet checked, with health record book to accompany them home on 8/7/26. Will include 1st distemper & dewormer.

ID Verified
Clarendon, PA
Mixed Breed dogs Blue - Ad 1
Mixed Breed dogs Blue - Ad 2
BOOST
21

Blue

Great Dane & Labrador Retriever hybrid

7 weeksAge
MaleSex
$800Price

Mother (Cami's) 2nd litter who is a Brindle Great Dane, Gentle, Great Mama, Very loving, obedient & loyal. All pups just like 1st litter will be vet checked, with health record book to accompany them home on 8/7/26. Will include 1st distemper & dewormer. These pups will be large & very loveable!

ID Verified
Clarendon, PA
Mixed Breed dogs Orange - Ad 1
Mixed Breed dogs Orange - Ad 2
BOOST
19

Orange

Great Dane & Labrador Retriever hybrid

7 weeksAge
FemaleSex
$800Price

Mother (Cami's) 2nd litter who is a Brindle Great Dane, Gentle, Great Mama, Very loving, obedient & loyal. All pups just like 1st litter will be vet checked, with health record book to accompany them home on 8/7/26. Will include 1st distemper & dewormer.

ID Verified
Clarendon, PA
Mixed Breed dogs Red - Ad 1
Mixed Breed dogs Red - Ad 2
BOOST
15

Red

Great Dane & Labrador Retriever hybrid

7 weeksAge
FemaleSex
$800Price

Mother (Cami's) 2nd litter who is a Brindle Great Dane, Gentle, Great Mama, Very loving, obedient & loyal. All pups just like 1st litter will be vet checked, with health record book to accompany them home on 8/7/26. Will include 1st distemper & dewormer.

ID Verified
Clarendon, PA
Daniff dogs Clover - Ad 1
Daniff dogs Clover - Ad 2
PRO
7

Clover

Daniff

10 weeksAge
FemaleSex
$2,500Price

Silver merle with blue eyes xxl mastiff loves to cuddle and give kisses

ID Verified
Princeton, MN
Mixed Breed dogs Purple - Ad 1
Mixed Breed dogs Purple - Ad 2
PRO
6

Purple

Great Dane & Goldendoodle hybrid

10 weeksAge
FemaleSex
$1,200Price

Purple is a brave young lady and our daughters favorite. She will sleep right next to you and is always the first to pop up and come see us when we enter the room. She is also %100 black. There are no

ID Verified
Essex Junction, VT
Transport
Mixed Breed dogs Milo - Ad 1
Mixed Breed dogs Milo - Ad 2
PRO
4

Milo

Dogue De Bordeaux & Great Dane hybrid

13 weeksAge
MaleSex
$600Price

Sweet

Williamsburg, IN
Transport
Daniff dogs Serenity - Ad 1
Daniff dogs Serenity - Ad 2
PRO
5

Serenity

Daniff

10 weeksAge
FemaleSex
$2,500Price

Silver merle with blue eyes xxl mastiff female loves to cuddle and give kisses

ID Verified
Princeton, MN
Daniff dogs Lester - Ad 1
Daniff dogs Lester - Ad 2
PRO
5

Lester

Daniff

10 weeksAge
MaleSex
$1,200Price

Blue with green eyes xxl mastiff male loves to cuddle and give kisses

ID Verified
Princeton, MN
Daniff dogs Smoke - Ad 1
Daniff dogs Smoke - Ad 2
PRO
6

Smoke

Daniff

10 weeksAge
MaleSex
$2,000Price

Blue merle with green eyes xxl mastiff male loves to cuddle and give kisses

ID Verified
Princeton, MN
Mixed Breed dogs Maddy - Ad 1
Mixed Breed dogs Maddy - Ad 2
PRO
5

Maddy

Dogue De Bordeaux & Great Dane hybrid

13 weeksAge
FemaleSex
$400Price

Sweet

Williamsburg, IN
Transport
Mixed Breed dogs Mixed Breed Puppy 1 - Ad 1
Mixed Breed dogs Mixed Breed Puppy 1 - Ad 2
ADVANCED
8

Mixed Breed Puppy 1

Mixed Breed & Great Dane hybrid

1 yearAge
MaleSex
$250Price

Meet Randy! This sweet, goofy, and loving boy who thinks he's smaller then what he is. He's a great cuddler who will find room for himself anywhere he can just to get next to you. He's great with othe

ID Verified
Windber, PA
Mixed Breed dogs Blue - Ad 13
BOOST
11

Blue

Great Dane & Labrador Retriever hybrid

8 weeksAge
MaleSex
$750Price

Blue has a beautiful Merle coat just like her Mom. We will update as time goes on!!!

ID Verified
Nassau, NY
Mixed Breed dogs Puppy 8 - Ad 14
BOOST
4

Puppy 8

Doberman Pinscher & Great Dane hybrid

10 weeksAge
FemaleSex
$500Price

Gorgeous big girl, fawn color. Biggest of the females!

ID Verified
Slippery Rock, PA
Transport
Mixed Breed dogs Brown - Ad 15
BOOST
12

Brown

Great Dane & Labrador Retriever hybrid

8 weeksAge
FemaleSex
$750Price

Brown has a beautiful Merle coat just like her Mom. We will update as time goes on!!!

ID Verified
Nassau, NY
Mixed Breed dogs Puppy 6 - Ad 16
BOOST
3

Puppy 6

Doberman Pinscher & Great Dane hybrid

10 weeksAge
MaleSex
$500Price

Handsome big boy, mantle color (black with white chest).

ID Verified
Slippery Rock, PA
Transport
Mixed Breed dogs Puppy 10 - Ad 17
BOOST
3

Puppy 10

Doberman Pinscher & Great Dane hybrid

10 weeksAge
FemaleSex
$500Price

Gorgeous little girl, fawn color with white chest.

ID Verified
Slippery Rock, PA
Transport
Mixed Breed dogs Puppy 5 - Ad 18
BOOST
3

Puppy 5

Doberman Pinscher & Great Dane hybrid

10 weeksAge
MaleSex
$500Price

Handsome big boy, fawn color. Biggest of the litter!

ID Verified
Slippery Rock, PA
Transport
Mixed Breed dogs Puppy 2 - Ad 19
BOOST
3

Puppy 2

Doberman Pinscher & Great Dane hybrid

10 weeksAge
MaleSex
$500Price

Handsome little boy, chocolate Merle.

ID Verified
Slippery Rock, PA
Transport
Mixed Breed dogs Puppy 4 - Ad 20
BOOST
3

Puppy 4

Doberman Pinscher & Great Dane hybrid

10 weeksAge
MaleSex
$500Price

Handsome big boy, blue Merle.

ID Verified
Slippery Rock, PA
Transport
Mixed Breed dogs Doberdane Tan/Wht M - Ad 21
16

Doberdane Tan/Wht M

Great Dane & Doberman Pinscher hybrid

4 monthsAge
MaleSex
$1,000Price

Doberdane puppies available. UTD vaccines and dewormings, 14 day parvo warranty and 2yr hip/genetics warranty included. Natural tail. Ear crop service available at an additional cost. Shipping also av

Maricopa, AZ
Transport
Mixed Breed dogs Doberdane Blk/Rst F - Ad 22
16

Doberdane Blk/Rst F

Great Dane & Doberman Pinscher hybrid

4 monthsAge
FemaleSex
$1,500Price

Doberdane puppies available. UTD vaccines and dewormings, 14 day parvo warranty and 2yr hip/genetics warranty included. Natural tail. Ear crop service available at an additional cost. Shipping also av

Maricopa, AZ
Transport
Mixed Breed dogs Doberdane Champagne F - Ad 23
20

Doberdane Champagne F

Great Dane & Doberman Pinscher hybrid

4 monthsAge
FemaleSex
$1,200Price

Doberdane puppies available. UTD vaccines and dewormings, 14 day parvo warranty and 2yr hip/genetics warranty included. Natural tail. Ear crop service available at an additional cost. Shipping also av

Maricopa, AZ
Transport
Mixed Breed dogs Doberdane (Madison) - Ad 24
19

Doberdane (Madison)

Great Dane & Doberman Pinscher hybrid

4 monthsAge
FemaleSex
$1,000Price

Doberdane puppies available. UTD vaccines and dewormings, 14 day parvo warranty and 2yr hip/genetics warranty included. Natural tail. Ear crop service available at an additional cost. Shipping also av

Maricopa, AZ
Transport
Great Danoodle dogs Great Danoodle 4 - Ad 25
3

Great Danoodle 4

Great Danoodle

15 weeksAge
FemaleSex
$1,000Price

Statues , loyal , affectionate and fast learning.

Ligonier, PA
Great Danoodle dogs Great Danoodle 5 - Ad 26
3

Great Danoodle 5

Great Danoodle

15 weeksAge
FemaleSex
$1,000Price

Statues , loyal , affectionate and fast learning.

Ligonier, PA
Great Danoodle dogs Great Danoodle 1 - Ad 27
3

Great Danoodle 1

Great Danoodle

15 weeksAge
FemaleSex
$1,000Price

Statues , loyal , affectionate and fast learning.

Ligonier, PA
Great Danoodle dogs Great Danoodle 3 - Ad 28
3

Great Danoodle 3

Great Danoodle

15 weeksAge
FemaleSex
$1,000Price

Statues , loyal , affectionate and fast learning.

Ligonier, PA
Mixed Breed dogs Yellow-Partial Brindle - Ad 1
Mixed Breed dogs Yellow-Partial Brindle - Ad 2
Reserved
BOOST
11

Yellow-Partial Brindle

Great Dane & Labrador Retriever hybrid

7 weeksAge
MaleSex
$1,500Price

Mother (Cami's) 2nd litter who is a Brindle Great Dane, Gentle, Great Mama, Very loving, obedient & loyal. All pups just like 1st litter will be vet checked, with health record book to accompany them home on 8/7/26. Will include 1st distemper & dewormer.

ID Verified
Clarendon, PA
Mixed Breed dogs Purple - Ad 1
Mixed Breed dogs Purple - Ad 2
Reserved
BOOST
17

Purple

Great Dane & Labrador Retriever hybrid

7 weeksAge
FemaleSex
$800Price

Mother (Cami's) 2nd litter who is a Brindle Great Dane, Gentle, Great Mama, Very loving, obedient & loyal. All pups just like 1st litter will be vet checked, with health record book to accompany them home on 8/7/26. Will include 1st distemper & dewormer.

ID Verified
Clarendon, PA
Mixed Breed dogs Puppy 3 - Ad 31
Reserved
BOOST
3

Puppy 3

Doberman Pinscher & Great Dane hybrid

10 weeksAge
MaleSex
$500Price

Handsome big boy, mantle color (black with white chest)

ID Verified
Slippery Rock, PA
Transport
Mixed Breed dogs Puppy 7 - Ad 32
Reserved
BOOST
3

Puppy 7

Doberman Pinscher & Great Dane hybrid

10 weeksAge
FemaleSex
$500Price

Gorgeous little girl, blue Merle.

ID Verified
Slippery Rock, PA
Transport
Mixed Breed dogs Puppy 1 - Ad 33
Reserved
BOOST
3

Puppy 1

Doberman Pinscher & Great Dane hybrid

10 weeksAge
FemaleSex
$500Price

Gorgeous little girl, blue Merle.

ID Verified
Slippery Rock, PA
Transport

FAQs

The average cost of a purebred Great Dane puppy in the United States is approximately $1433, though prices can vary based on factors such as pedigree, breeder reputation, and location.