Great Dane Puppies for sale in Buffalo, New York

Euro Lines AKC registered Vet checked First round of vaccinations dewormed and flea and tick treatment. This little cutie is calm and laid back.

WENNY 💜 Reverse Brindle Female Purple Collar ☂️ Our biggest girl, Wenny, has an equally big love for attention, food and cuddles. Her striking reverse-brindle coat makes her stand out immediately, b

HONEY 🍯 Brindle Female Sunshine Yellow Collar 💛 Honey is every bit as sweet as her name - with a spirited side to match! This affectionate girl has blossomed into a confident puppy, bringing pl

MIAMI 🦩 Brindle Female Hot Pink Collar 💕 Miami has a little extra sparkle in her personality! Playful, spirited and always ready to capture your attention, she knows how to make her presence. She b

Meet your ultimate gentle giant and loyal companion, Lola! We are thrilled to introduce our magnificent, athletic, black with a white stomach and deeply devoted Great Dane puppy, ready to bring majest

Meet your ultimate gentle giant and loyal companion, Lacie! We are thrilled to introduce our magnificent, athletic, black colored and deeply devoted Great Dane puppy, ready to bring majesty, affection

Playful and social

Playful and social

Playful and social

Hello, I am sadie, a sweet cuddly Great Dane puppy! I am looking for my new forever home. I am ready to go home with you now! I will be AKC registered, up to date on vaccines, and also am that checked

Say hello to Tulip! This darling Great Dane puppy is one of a kind and ready to adventure with you. She is family raised with children and is extra spoiled with love and attention. She will be vet che

I am shy at first but I worm up quickly. I love to cuddle. I am paper trained. I come when called.

This beautiful brindle male is the last of his litter. He is potty trained, crate trained, and well socialized with children (ages 2–15) and other animals. He is ready for his new home today. -Lancast

Hello, I am Trevor.. a sweet cuddly Great Dane puppy! I am looking for my new forever home. I am ready to go home with you now! I will be AKC registered, up to date on vaccines, and also am that check

Female she is ready for her forever home

Winnie, sweet and lovable always up for cuddles. She is very playful and if you want a cuddle buddy to sit and watch TV with she is your gal.

Winnie, sweet and lovable always up for cuddles. She is very playful and if you want a cuddle buddy to sit and watch TV with she is your gal.

Winnie, sweet and lovable always up for cuddles. She is very playful and if you want a cuddle buddy to sit and watch TV with she is your gal.

Winnie, sweet and lovable always up for cuddles. She is very playful and if you want a cuddle buddy to sit and watch TV with she is your gal.

Winnie, sweet and lovable always up for cuddles. She is very playful and if you want a cuddle buddy to sit and watch TV with she is your gal.

Winnie, sweet and lovable always up for cuddles. She is very playful and if you want a cuddle buddy to sit and watch TV with she is your gal.

Winnie, sweet and lovable always up for cuddles. She is very playful and if you want a cuddle buddy to sit and watch TV with she is your gal.

Draco is a blue brindle! very chill and layed back boy! He loves his food and has the most gorgeous head! Waiting for that perfect family ❤️ All of our puppy's get ENS training all are raised in our

We are a small, family-centered breeder who absolutely loves raising our Great Dane puppies and helping match them with their perfect forever families. Our Dame and Sire are both AKC registered and, more importantly, they're part of our everyday life—these puppies are raised right in our home with lots of love and attention. Our pups are handled daily, well socialized, and

We are a small, family-centered breeder who absolutely loves raising our Great Dane puppies and helping match them with their perfect forever families. Our Dame and Sire are both AKC registered and, more importantly, they're part of our everyday life—these puppies are raised right in our home with lots of love and attention. Our pups are handled daily, well socialized, and

We are a small, family-centered breeder who absolutely loves raising our Great Dane puppies and helping match them with their perfect forever families. Our Dame and Sire are both AKC registered and, more importantly, they're part of our everyday life—these puppies are raised right in our home with lots of love and attention. Our pups are handled daily, well socialized, and

We are a small, family-centered breeder who absolutely loves raising our Great Dane puppies and helping match them with their perfect forever families. Our Dame and Sire are both AKC registered and, more importantly, they're part of our everyday life—these puppies are raised right in our home with lots of love and attention. Our pups are handled daily, well socialized, and

Lavender Merle

Xenia has a solid black coat. She was the first born on this litter and wants to be part of your pack. Misty welcomed 10 beautiful, healthy puppies into the world on July 18, 2026. 7 females and 3

Stunning blue female puppy well socialized would children and other pets will be up to date on vaccines deworming and flea preventative will also be going home with her puppy starter kit started on po

Merlequin with icy blue eyes. 4 distinct colors with every shade in between! Beautiful dog

Fawn

Reverse brindle

Diva s a stunning blue female can be registered threw AKC is well socialized with children and other pets plus every family life. Will have her 1st vaccines and dewormings go to her new family with al

Blue brindle mantle female 5lbs at 2 weeks old

Brindle merle female 5lbs at 2 weeks old

Blue brindle merle male 5lbs at 2 weeks old

Fury has a reverse brindle coat. She is a sweet puppy and is looking for a family to love her.

Brindle Merle male 5lbs at 2 weeks old

Brindlequin female 5lbs at 2 weeks old

June has white toes on back feet. She is playful and loves to cuddle.

Luna is all black with white chest and two white toes. She loves to cuddle.